Very cool demo!
Good points:

- Each tile having a unique effect

- Meeting and recruiting party members and musicians

- Helping people out because it feels nice :)

- Lovely painterly art

- Naturalistic sound design for each arena

Criticisms:

- Some tiles blend together and look similar (Brickie bricks and brown chests are easy to mix up)

- It can be hard to read enemy stat boxes as their mouse-over regions are very large and overlap

- Feels like a lot of enemies are either too easy to beat, or do so much damage they're nearly impossible. Maybe some could move tiles themselves to be more active challenges?

Overall very promising, I'm looking forward to seeing how this progresses!